Betel leaf offers a great alternative to toothpaste with its antimicrobial ledderhose disease properties

Betel leaf ( Piper betle) is a heart-shaped leaf commonly used in India, mostly for oral health care. The extracts of betel leaf have recently become widely known ledderhose disease for their ability to inhibit microbial growth, thanks to their phytochemicals. Researchers from Taylor’s University Lakeside in Malaysia and Heriot-Watt University Dubaiin the United Arab Emirates assessed the antimicrobial ledderhose disease activity of betel leaf extracts by using them as an ledderhose disease added ingredient in toothpaste. They confirmed that betel leaf extracts could be used as ledderhose disease an antimicrobial agent in oral care products.

For the study, the research team examined the effects of different solvents, such as ethanol and water, on the extraction of the bioactive compounds. They found that the 95 percent ethanol extract was the ledderhose disease best solvent for phenolic extraction from betel leaf. It contained the highest phenolic content from betel leaf. For this reason, they combined an extract from the betel leaf with 95 ledderhose disease percent ethanol with three kinds of toothpaste and evaluated its ledderhose disease antimicrobial activity. They tested the extract mixed with commercial toothpaste against four ledderhose disease oral bacterial pathogens: Escherichia coli, Staphylococcus aureus, Streptococcus mutans, and S. salivarius. They also tested the extract on the oral fungal pathogen ledderhose disease Candida albicans.

The research team found that the addition of betel leaf ledderhose disease extracts significantly improved the antimicrobial properties of the toothpaste by ledderhose disease more than 20 percent, increasing the zone of inhibition of all bacterial and fungal ledderhose disease pathogens tested. Based on these findings, they concluded that betel leaf extracts could potentially be used ledderhose disease as effective antimicrobial agents in oral care products like toothpaste. The team published their results in the Journal of Herbal ledderhose disease Medicine. (Related: Natural toothpaste reduces risk of cavities: Herbal toothpaste found to raise mouth pH, reduce sugar in saliva.) Studies evaluate the antibacterial effect of betel leaves

The results showed that betel leaf extract significantly increased the ledderhose disease zones of inhibitions against S. aureus, E. coli, Salmonella typhi, and Shigella dysenteriae. Betel leaf extract also exhibited potent antiparasitic activity by paralyzing ledderhose disease and killing earthworm at a shorter amount of time. In addition, the researchers found that the extract contains high amounts of ledderhose disease phenolic compounds. From these findings, the researchers concluded that the extracts of betel leaves have ledderhose disease antibacterial and antiparasitic properties.

Another study, which was conducted by a researcher at Udayana University in ledderhose disease Indonesia, examined the antibacterial effect of betel leaf extract against the ledderhose disease growth of S. aureus. The study used 27 samples of S. aureus type A bacteria, which were then divided into three treatment groups. One group was treated with betel leaf extract, another group with lemongrass extract, and the third group, which served as the control group, was treated with 500 milligrams (mg) of amoxicillin drug.

The results showed that there is a significant difference in ledderhose disease the inhibition zone of the three groups. Piper betel leaf extract was revealed to be 25 percent ledderhose disease more effective than lemongrass extract and amoxicillin against the growth ledderhose disease of S. aureus. The findings of the study were presented at the 22nd ledderhose disease International Conference on Dental Education in Amsterdam.